Makihara and Nagaoka were once handshaker partners with each other. They also worked together to study about handshakers. They had a very good relationship with each other until the sudden disaperances of their two professors leaving them along with their two twin daughters. Nagaoka suddenly went haywire taking one of the twins. Makihara and Nagaoka lost their relationship with each other ending their role as handshakers.

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